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Role of proteolytic enzymes in human prostate bone metastasis formation: in vivo and in vitro studies
Prostate cancers ability to invade and grow in bone marrow stroma is thought to be due in part to degradative enzymes. The formation of prostate skeletal metastases have been reproduced in vitro by growing co-cultures of prostatic epithelial cells in bone marrow stroma. Expression of urokinase plasm...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364179/ https://www.ncbi.nlm.nih.gov/pubmed/11953862 http://dx.doi.org/10.1038/sj.bjc.6600207 |