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Mechanisms of nordihydroguaiaretic acid-induced growth inhibition and apoptosis in human cancer cells

Lipoxygenase metabolites of arachidonic acid can act as growth promoting factors for various cancer cell lines. Here we demonstrate that the 5-lipoxygenase inhibitor nordihydroguaiaretic acid potently inhibits anchorage-independent growth of human pancreatic and cervical cancer cells in soft agar an...

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Detalles Bibliográficos
Autores principales:	Seufferlein, T, Seckl, M J, Schwarz, E, Beil, M, v Wichert, G, Baust, H, Lührs, H, Schmid, R M, Adler, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364182/ https://www.ncbi.nlm.nih.gov/pubmed/11953870 http://dx.doi.org/10.1038/sj.bjc.6600186

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