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Integrin αvβ6-associated ERK2 mediates MMP-9 secretion in colon cancer cells

There is general consensus that matrix metalloproteinases are involved in tumour progression. We show herein that inhibition of integrin αvβ6 expression in colon cancer cells suppresses MMP-9 secretion. This integrin-mediated event is dependent upon direct binding between the β6 integrin subunit and...

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Detalles Bibliográficos
Autores principales:	Gu, X, Niu, J, Dorahy, D J, Scott, R, Agrez, M V
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364215/ https://www.ncbi.nlm.nih.gov/pubmed/12177807 http://dx.doi.org/10.1038/sj.bjc.6600480

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