Cargando…

Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis

Angiogenesis is a prerequisite for tumour progression and is highly regulated by growth factors and cytokines a number of which also stimulate the production of nitric oxide. Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthesis. Asymmetric dimethylarginine is metabolised...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kostourou, V, Robinson, S P, Cartwright, J E, Whitley, G St J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364234/ https://www.ncbi.nlm.nih.gov/pubmed/12237779 http://dx.doi.org/10.1038/sj.bjc.6600518

Ejemplares similares

The role of tumour-derived iNOS in tumour progression and angiogenesis
por: Kostourou, V, et al.
Publicado: (2011)

A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase
por: Ragavan, Vinitha N., et al.
Publicado: (2023)

Dimethylarginine dimethylaminohydrolase 2 promotes tumor angiogenesis in lung adenocarcinoma
por: Shiozawa, Toshihiro, et al.
Publicado: (2015)

Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis
por: Lange, Clemens, et al.
Publicado: (2016)

Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity
por: D'Mello, Richard, et al.
Publicado: (2015)

Divergent Dimethylarginine Dimethylaminohydrolase Isoenzyme Expression in the Central Nervous System
por: Kozlova, Alena A., et al.
Publicado: (2021)

A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1
por: Buijs, Nikki, et al.
Publicado: (2017)

Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation
por: Xie, Ziang, et al.
Publicado: (2022)

Inhibition of Dimethylarginine Dimethylaminohydrolase (DDAH) Enzymes as an Emerging Therapeutic Strategy to Target Angiogenesis and Vasculogenic Mimicry in Cancer
por: Hulin, Julie-Ann, et al.
Publicado: (2020)

Arginine deiminase: a potential inhibitor of angiogenesis and tumour growth
por: Park, I-S, et al.
Publicado: (2003)

Dimethylarginine Dimethylaminohydrolase-1 Transgenic Mice Are Not Protected from Ischemic Stroke
por: Leypoldt, Frank, et al.
Publicado: (2009)

Ligand-Dependent Dynamics of the Active-Site Lid in Bacterial Dimethylarginine Dimethylaminohydrolase
por: Rasheed, Masooma, et al.
Publicado: (2014)

Inhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and Development
por: Murphy, Rhys B., et al.
Publicado: (2016)

Regulation of dimethylarginine dimethylaminohydrolase 2 expression by NF-κB acetylation
por: Li, Jiaqi, et al.
Publicado: (2021)

Dietary restriction reduces angiogenesis and growth in an orthotopic mouse brain tumour model
por: Mukherjee, P, et al.
Publicado: (2002)

A Functional Variant of the Dimethylarginine Dimethylaminohydrolase-2 Gene Is Associated with Insulin Sensitivity
por: Andreozzi, Francesco, et al.
Publicado: (2012)

Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance
por: Tommasi, S., et al.
Publicado: (2017)

Overexpression of Dimethylarginine Dimethylaminohydrolase 1 Attenuates Airway Inflammation in a Mouse Model of Asthma
por: Kinker, Kayla G., et al.
Publicado: (2014)

Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis
por: Duda, D G, et al.
Publicado: (2002)

Exploring the role of dimethylarginine dimethylaminohydrolase-mediated reduction in tissue asymmetrical dimethylarginine levels in cardio-protective mechanism of ischaemic postconditioning in rats
por: Kaur, Kamaldeep, et al.
Publicado: (2019)

n-3 Polyunsaturated fatty acids decrease mucosal/epidermal reactions and enhance antitumour effect of ionising radiation with inhibition of tumour angiogenesis
por: Wen, B, et al.
Publicado: (2003)

Thiram inhibits angiogenesis and slows the development of experimental tumours in mice
por: Marikovsky, M
Publicado: (2002)

Cerebral Changes Occurring in Arginase and Dimethylarginine Dimethylaminohydrolase (DDAH) in a Rat Model of Sleeping Sickness
por: Amrouni, Donia, et al.
Publicado: (2011)

The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study
por: Lu, Tse-Min, et al.
Publicado: (2011)

Inhibition of the alpha-ν integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo
por: Buerkle, M A, et al.
Publicado: (2002)

Dimethylarginine Dimethylaminohydrolase1 Is an Organ-Specific Mediator of End Organ Damage in a Murine Model of Hypertension
por: Sydow, Karsten, et al.
Publicado: (2012)

Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1
por: Wang, Ying, et al.
Publicado: (2021)

Periodate-treated, non-anticoagulant heparin-carrying polystyrene (NAC-HCPS) affects angiogenesis and inhibits subcutaneous induced tumour growth and metastasis to the lung
por: Ono, K, et al.
Publicado: (2002)

Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis
por: Park, K, et al.
Publicado: (2009)

Dimethylarginine Dimethylaminohydrolase 2 (DDAH 2) Gene Polymorphism, Asymmetric Dimethylarginine (ADMA) Concentrations, and Risk of Coronary Artery Disease: A Case-Control Study
por: Xuan, Chao, et al.
Publicado: (2016)

PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer
por: Su, Y, et al.
Publicado: (2010)

A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients
por: Mannino, Gaia Chiara, et al.
Publicado: (2019)

Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis
por: Chertow, Jessica H., et al.
Publicado: (2015)

Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis
por: Hardee, M E, et al.
Publicado: (2005)

Inhibition of renal cell carcinoma angiogenesis and growth by antisense oligonucleotides targeting vascular endothelial growth factor
por: Shi, W, et al.
Publicado: (2002)

MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1
por: Hulin, Julie-Ann, et al.
Publicado: (2017)

Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer
por: Connolly, E M, et al.
Publicado: (2002)

A novel hypoxia-dependent 2-nitroimidazole KIN-841 inhibits tumour-specific angiogenesis by blocking production of angiogenic factors
por: Shimamura, M, et al.
Publicado: (2003)

Fibrinogen E fragment selectively disrupts the vasculature and inhibits the growth of tumours in a syngeneic murine model
por: Brown, N J, et al.
Publicado: (2002)

Carboxymethyl benzylamide dextran inhibits angiogenesis and growth of VEGF-overexpressing human epidermoid carcinoma xenograft in nude mice
por: Hamma-Kourbali, Y, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_fsuj1tcbvdf5ss7t5ok7crjimq