Increased aquaporin 1 water channel expression inhuman brain tumours

Aquaporin 1 is a water channel protein. There was little aquaporin 1 immunoreactivity in normal brain parenchyma. In astrocytomas, aquaporin 1 was expressed in microvessel endothelia and neoplastic astrocytes. In metastatic carcinomas, aquaporin 1 was present in microvessel endothelia and reactive a...

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Detalles Bibliográficos
Autores principales: Saadoun, S, Papadopoulos, M C, Davies, D C, Bell, B A, Krishna, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Molecular and Cellular Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364235/
https://www.ncbi.nlm.nih.gov/pubmed/12237771
http://dx.doi.org/10.1038/sj.bjc.6600512
Descripción
Sumario:Aquaporin 1 is a water channel protein. There was little aquaporin 1 immunoreactivity in normal brain parenchyma. In astrocytomas, aquaporin 1 was expressed in microvessel endothelia and neoplastic astrocytes. In metastatic carcinomas, aquaporin 1 was present in microvessel endothelia and reactive astrocytes. Aquaporin 1 may participate in the formation of brain tumour oedema. British Journal of Cancer (2002) 21, 621–623. doi:10.1038/sj.bjc.6600512 www.bjcancer.com © 2002 Cancer Research UK

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