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Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy

Cytochrome P450 3A is a drug-metabolising enzyme activity due to CYP3A4 and CYP3A5 gene products, that is involved in the inactivation of anticancer drugs. This study analyses the potential of cytochrome P450 3A enzyme in human colorectal cancer to impact anticancer therapy with drugs that are cytoc...

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Detalles Bibliográficos
Autores principales:	Martínez, C, García-Martín, E, Pizarro, R M, García-Gamito, F J, Agúndez, J A G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2002
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364247/ https://www.ncbi.nlm.nih.gov/pubmed/12237780 http://dx.doi.org/10.1038/sj.bjc.6600494

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