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Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death

Nutrient deprivation has been shown to cause cancer cell death. To exploit nutrient deprivation as anti-cancer therapy, we investigated the effects of the anti-metabolite 2-deoxy-D-glucose on breast cancer cells in vitro. This compound has been shown to inhibit glucose metabolism. Treatment of human...

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Detalles Bibliográficos
Autores principales: Aft, R L, Zhang, F W, Gius, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364258/
https://www.ncbi.nlm.nih.gov/pubmed/12232767
http://dx.doi.org/10.1038/sj.bjc.6600547

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