A prospective cohort study of soy product intake and stomach cancer death

The relationship between intake of soy products and death from stomach cancer was examined in a community-based prospective study of Japanese men and women in Takayama, Japan. Over 7 years of follow-up, 121 deaths from stomach cancer (81 men and 40 women) occurred among 30 304 (13 880 men and 16 424...

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Autores principales: Nagata, C, Takatsuka, N, Kawakami, N, Shimizu, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364290/
https://www.ncbi.nlm.nih.gov/pubmed/12085252
http://dx.doi.org/10.1038/sj.bjc.6600349
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author Nagata, C
Takatsuka, N
Kawakami, N
Shimizu, H
author_facet Nagata, C
Takatsuka, N
Kawakami, N
Shimizu, H
author_sort Nagata, C
collection PubMed
description The relationship between intake of soy products and death from stomach cancer was examined in a community-based prospective study of Japanese men and women in Takayama, Japan. Over 7 years of follow-up, 121 deaths from stomach cancer (81 men and 40 women) occurred among 30 304 (13 880 men and 16 424 women) participants who were at least 35 years of age. Diet including the intake of soy products and isoflavones was assessed by a validated semiquantitative food–frequency questionnaire at the beginning of the study. In men, the highest compared to the lowest tertile of total soy product intake was significantly inversely associated with death from stomach cancer after controlling for covariates (hazard ratios=0.50; 95% confidence intervals (CIs) 0.26-0.93, P for trend=0.03). Decreased hazard ratios for the highest compared to the lowest tertiles of total soy product intake (hazard ratios=0.49; 95% CI 0.22–1.13) was observed in women, although this association was of marginal significance. These data suggest that soy intake may reduce the risk of death from stomach cancer. British Journal of Cancer (2002) 87, 31–36. doi:10.1038/sj.bjc.6600349 www.bjcancer.com © 2002 Cancer Research UK
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spelling pubmed-23642902009-09-10 A prospective cohort study of soy product intake and stomach cancer death Nagata, C Takatsuka, N Kawakami, N Shimizu, H Br J Cancer Epidemiology The relationship between intake of soy products and death from stomach cancer was examined in a community-based prospective study of Japanese men and women in Takayama, Japan. Over 7 years of follow-up, 121 deaths from stomach cancer (81 men and 40 women) occurred among 30 304 (13 880 men and 16 424 women) participants who were at least 35 years of age. Diet including the intake of soy products and isoflavones was assessed by a validated semiquantitative food–frequency questionnaire at the beginning of the study. In men, the highest compared to the lowest tertile of total soy product intake was significantly inversely associated with death from stomach cancer after controlling for covariates (hazard ratios=0.50; 95% confidence intervals (CIs) 0.26-0.93, P for trend=0.03). Decreased hazard ratios for the highest compared to the lowest tertiles of total soy product intake (hazard ratios=0.49; 95% CI 0.22–1.13) was observed in women, although this association was of marginal significance. These data suggest that soy intake may reduce the risk of death from stomach cancer. British Journal of Cancer (2002) 87, 31–36. doi:10.1038/sj.bjc.6600349 www.bjcancer.com © 2002 Cancer Research UK Nature Publishing Group 2002-07-01 2002-07-15 /pmc/articles/PMC2364290/ /pubmed/12085252 http://dx.doi.org/10.1038/sj.bjc.6600349 Text en Copyright © 2002 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiology
Nagata, C
Takatsuka, N
Kawakami, N
Shimizu, H
A prospective cohort study of soy product intake and stomach cancer death
title A prospective cohort study of soy product intake and stomach cancer death
title_full A prospective cohort study of soy product intake and stomach cancer death
title_fullStr A prospective cohort study of soy product intake and stomach cancer death
title_full_unstemmed A prospective cohort study of soy product intake and stomach cancer death
title_short A prospective cohort study of soy product intake and stomach cancer death
title_sort prospective cohort study of soy product intake and stomach cancer death
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364290/
https://www.ncbi.nlm.nih.gov/pubmed/12085252
http://dx.doi.org/10.1038/sj.bjc.6600349
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