Novel substituted methylenedioxy lignan suppresses proliferation of cancer cells by inhibiting telomerase and activation of c-myc and caspases leading to apoptosis

Conventional solvent fractionation and bioactivity based target assays were used to identify a new anti-cancer molecule from Phyllanthus urinaria, a herbal medicinal plant used in South India. At each step of the purification process the different fractions that were isolated were tested for specifi...

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Detalles Bibliográficos
Autores principales: Giridharan, P, Somasundaram, S T, Perumal, K, Vishwakarma, R A, Karthikeyan, N P, Velmurugan, R, Balakrishnan, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364294/
https://www.ncbi.nlm.nih.gov/pubmed/12085264
http://dx.doi.org/10.1038/sj.bjc.6600422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364294/
https://www.ncbi.nlm.nih.gov/pubmed/12085264
http://dx.doi.org/10.1038/sj.bjc.6600422

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