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Novel substituted methylenedioxy lignan suppresses proliferation of cancer cells by inhibiting telomerase and activation of c-myc and caspases leading to apoptosis
Conventional solvent fractionation and bioactivity based target assays were used to identify a new anti-cancer molecule from Phyllanthus urinaria, a herbal medicinal plant used in South India. At each step of the purification process the different fractions that were isolated were tested for specifi...
Autores principales: | Giridharan, P, Somasundaram, S T, Perumal, K, Vishwakarma, R A, Karthikeyan, N P, Velmurugan, R, Balakrishnan, A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364294/ https://www.ncbi.nlm.nih.gov/pubmed/12085264 http://dx.doi.org/10.1038/sj.bjc.6600422 |
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