Lewis Phenotype in Women With Preterm Labor and Premature Rupture of the Membranes

Objective: The purpose of this study was to evaluate the possible association between Lewis phenotype status in pregnant women and preterm labor (PTL) or preterm rupture of the membranes (PROM). Methods: Red blood cell (RBC) Lewis phenotype was determined in 113 pregnant women admitted for PTL or PR...

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Detalles Bibliográficos
Autores principales: O'Brien, William F., Leparc, German F., Holbrook, Jodi
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1995
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364422/
https://www.ncbi.nlm.nih.gov/pubmed/18476021
http://dx.doi.org/10.1155/S1064744995000329
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author O'Brien, William F.
Leparc, German F.
Holbrook, Jodi
author_facet O'Brien, William F.
Leparc, German F.
Holbrook, Jodi
author_sort O'Brien, William F.
collection PubMed
description Objective: The purpose of this study was to evaluate the possible association between Lewis phenotype status in pregnant women and preterm labor (PTL) or preterm rupture of the membranes (PROM). Methods: Red blood cell (RBC) Lewis phenotype was determined in 113 pregnant women admitted for PTL or PROM and in 121 controls. The results were controlled for the influence of race on Lewis phenotype. Results: Pregnancy was associated with a higher frequency in women with the a–b– phenotype. There was no association between RBC Lewis phenotype and the occurrence of PTL or PROM. Conclusions: A susceptibility to PTL or PROM is not due to a lack of Lewis antigen expression on the plasma membrane of the vaginal mucosa.
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spelling pubmed-23644222008-05-12 Lewis Phenotype in Women With Preterm Labor and Premature Rupture of the Membranes O'Brien, William F. Leparc, German F. Holbrook, Jodi Infect Dis Obstet Gynecol Research Article Objective: The purpose of this study was to evaluate the possible association between Lewis phenotype status in pregnant women and preterm labor (PTL) or preterm rupture of the membranes (PROM). Methods: Red blood cell (RBC) Lewis phenotype was determined in 113 pregnant women admitted for PTL or PROM and in 121 controls. The results were controlled for the influence of race on Lewis phenotype. Results: Pregnancy was associated with a higher frequency in women with the a–b– phenotype. There was no association between RBC Lewis phenotype and the occurrence of PTL or PROM. Conclusions: A susceptibility to PTL or PROM is not due to a lack of Lewis antigen expression on the plasma membrane of the vaginal mucosa. Hindawi Publishing Corporation 1995 /pmc/articles/PMC2364422/ /pubmed/18476021 http://dx.doi.org/10.1155/S1064744995000329 Text en Copyright © 1995 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
O'Brien, William F.
Leparc, German F.
Holbrook, Jodi
Lewis Phenotype in Women With Preterm Labor and Premature Rupture of the Membranes
title Lewis Phenotype in Women With Preterm Labor and Premature Rupture of the Membranes
title_full Lewis Phenotype in Women With Preterm Labor and Premature Rupture of the Membranes
title_fullStr Lewis Phenotype in Women With Preterm Labor and Premature Rupture of the Membranes
title_full_unstemmed Lewis Phenotype in Women With Preterm Labor and Premature Rupture of the Membranes
title_short Lewis Phenotype in Women With Preterm Labor and Premature Rupture of the Membranes
title_sort lewis phenotype in women with preterm labor and premature rupture of the membranes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364422/
https://www.ncbi.nlm.nih.gov/pubmed/18476021
http://dx.doi.org/10.1155/S1064744995000329
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AT holbrookjodi lewisphenotypeinwomenwithpretermlaborandprematureruptureofthemembranes

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