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Human Immunodeficiency Virus-Associated Nephropathy in Pregnancy

Background: Human immunodeficiency virus (HIV)-associated nephropathy typically leads to endstage renal disease requiring dialysis within 3–4 months. This report describes the prenatal course of a patient with HIV-associated nephropathy requiring dialysis during pregnancy. Case: A 23-year-old nullip...

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Detalles Bibliográficos
Autores principales: Eriksen, Nancy L., Mastrobattista, Joan M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364478/
https://www.ncbi.nlm.nih.gov/pubmed/18476073
http://dx.doi.org/10.1155/S1064744996000191
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author Eriksen, Nancy L.
Mastrobattista, Joan M.
author_facet Eriksen, Nancy L.
Mastrobattista, Joan M.
author_sort Eriksen, Nancy L.
collection PubMed
description Background: Human immunodeficiency virus (HIV)-associated nephropathy typically leads to endstage renal disease requiring dialysis within 3–4 months. This report describes the prenatal course of a patient with HIV-associated nephropathy requiring dialysis during pregnancy. Case: A 23-year-old nulliparous, black female presented at 13 weeks gestation with a history of HIV-associated nephropathy and anemia. She had a CD4 count of 350/mm(3), a total urinary protein of 1.7 g/day, and a serum creatinine of 4.8 mg/dl. The patient was begun on zidovudine, 500 mg daily, and erythropoietin, 4,000 units weekly. At 23 weeks gestation, when she developed hypertension, a total urinary protein of 3.4 g/day, and a serum creatinine of 4.4 mg/dl, she was hospitalized. Her renal function continued to deteriorate, requiring hemodialysis. At 29-4/7 weeks, she developed preterm labor, for which she was placed on indomethacin. Four days later, at 30 weeks gestation, she delivered a viable male infant. Conclusion: HIV-associated nephropathy during pregnancy can be successfully managed with hemodialysis.
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spelling pubmed-23644782008-05-12 Human Immunodeficiency Virus-Associated Nephropathy in Pregnancy Eriksen, Nancy L. Mastrobattista, Joan M. Infect Dis Obstet Gynecol Research Article Background: Human immunodeficiency virus (HIV)-associated nephropathy typically leads to endstage renal disease requiring dialysis within 3–4 months. This report describes the prenatal course of a patient with HIV-associated nephropathy requiring dialysis during pregnancy. Case: A 23-year-old nulliparous, black female presented at 13 weeks gestation with a history of HIV-associated nephropathy and anemia. She had a CD4 count of 350/mm(3), a total urinary protein of 1.7 g/day, and a serum creatinine of 4.8 mg/dl. The patient was begun on zidovudine, 500 mg daily, and erythropoietin, 4,000 units weekly. At 23 weeks gestation, when she developed hypertension, a total urinary protein of 3.4 g/day, and a serum creatinine of 4.4 mg/dl, she was hospitalized. Her renal function continued to deteriorate, requiring hemodialysis. At 29-4/7 weeks, she developed preterm labor, for which she was placed on indomethacin. Four days later, at 30 weeks gestation, she delivered a viable male infant. Conclusion: HIV-associated nephropathy during pregnancy can be successfully managed with hemodialysis. Hindawi Publishing Corporation 1996 /pmc/articles/PMC2364478/ /pubmed/18476073 http://dx.doi.org/10.1155/S1064744996000191 Text en Copyright © 1996 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Eriksen, Nancy L.
Mastrobattista, Joan M.
Human Immunodeficiency Virus-Associated Nephropathy in Pregnancy
title Human Immunodeficiency Virus-Associated Nephropathy in Pregnancy
title_full Human Immunodeficiency Virus-Associated Nephropathy in Pregnancy
title_fullStr Human Immunodeficiency Virus-Associated Nephropathy in Pregnancy
title_full_unstemmed Human Immunodeficiency Virus-Associated Nephropathy in Pregnancy
title_short Human Immunodeficiency Virus-Associated Nephropathy in Pregnancy
title_sort human immunodeficiency virus-associated nephropathy in pregnancy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364478/
https://www.ncbi.nlm.nih.gov/pubmed/18476073
http://dx.doi.org/10.1155/S1064744996000191
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