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Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation

Background: The incidence of genital herpes simplex virus (HSV) has increased in recent years, particularly among women of reproductive age. This places more neonates at risk for severe morbidity and mortality. Treatment recommendations for primary disease in pregnancy are lacking, particularly for...

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Detalles Bibliográficos
Autores principales: Joffe, G. M., Olson, K., Merlin, T. L., Brown, A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364593/
https://www.ncbi.nlm.nih.gov/pubmed/18476192
http://dx.doi.org/10.1155/S1064744997000690
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author Joffe, G. M.
Olson, K.
Merlin, T. L.
Brown, A.
author_facet Joffe, G. M.
Olson, K.
Merlin, T. L.
Brown, A.
author_sort Joffe, G. M.
collection PubMed
description Background: The incidence of genital herpes simplex virus (HSV) has increased in recent years, particularly among women of reproductive age. This places more neonates at risk for severe morbidity and mortality. Treatment recommendations for primary disease in pregnancy are lacking, particularly for those who acquire. HSV remote from term. Case: A patient at 17 weeks of gestation carrying dichorionic twins developed primary herpes with subsequent vertical transmission of the virus and significant neonatal morbidity. Conclusion: Data regarding risks and benefits of treatments such as acyclovir and immunoprophylaxis are lacking at a time when the incidence of HSV infection is on the rise.
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spelling pubmed-23645932008-05-12 Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation Joffe, G. M. Olson, K. Merlin, T. L. Brown, A. Infect Dis Obstet Gynecol Research Article Background: The incidence of genital herpes simplex virus (HSV) has increased in recent years, particularly among women of reproductive age. This places more neonates at risk for severe morbidity and mortality. Treatment recommendations for primary disease in pregnancy are lacking, particularly for those who acquire. HSV remote from term. Case: A patient at 17 weeks of gestation carrying dichorionic twins developed primary herpes with subsequent vertical transmission of the virus and significant neonatal morbidity. Conclusion: Data regarding risks and benefits of treatments such as acyclovir and immunoprophylaxis are lacking at a time when the incidence of HSV infection is on the rise. Hindawi Publishing Corporation 1997 /pmc/articles/PMC2364593/ /pubmed/18476192 http://dx.doi.org/10.1155/S1064744997000690 Text en Copyright © 1997 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Joffe, G. M.
Olson, K.
Merlin, T. L.
Brown, A.
Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation
title Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation
title_full Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation
title_fullStr Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation
title_full_unstemmed Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation
title_short Vertical Transmission of Herpes Simplex Virus Acquired After Primary Outbreak in Second Trimester of a Dichorionic Twin Gestation
title_sort vertical transmission of herpes simplex virus acquired after primary outbreak in second trimester of a dichorionic twin gestation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364593/
https://www.ncbi.nlm.nih.gov/pubmed/18476192
http://dx.doi.org/10.1155/S1064744997000690
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