MGluR5 Mediates the Interaction between Late-LTP, Network Activity, and Learning

Hippocampal synaptic plasticity and learning are strongly regulated by metabotropic glutamate receptors (mGluRs) and particularly by mGluR5. Here, we investigated the mechanisms underlying mGluR5-modulation of these phenomena. Prolonged pharmacological blockade of mGluR5 with MPEP produced a profoun...

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Detalles Bibliográficos
Autores principales: Bikbaev, Arthur, Neyman, Sergey, Ngomba, Richard Teke, Conn, Jeffrey, Nicoletti, Ferdinando, Manahan-Vaughan, Denise
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364645/
https://www.ncbi.nlm.nih.gov/pubmed/18478073
http://dx.doi.org/10.1371/journal.pone.0002155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364645/
https://www.ncbi.nlm.nih.gov/pubmed/18478073
http://dx.doi.org/10.1371/journal.pone.0002155

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