Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study

A dose-finding study was undertaken to determine the maximum-tolerated dose, and the recommended dose of docetaxel in combination with 12-h timed (22:00–10:00) flat infusion of 5-fluorouracil (5-FU) in metastatic breast cancer patients. This schedule seems to reduce the occurrence of stomatitis of t...

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Autores principales: Ficorella, C, Morelli, M F, Ricevuto, E, Cannita, K, Porzio, G, Baldi, P Lanfiuti, Cianci, G, Rocco, ZC Di, Natoli, C, Tinari, N, Galitiis, F De, Calista, F, Marchetti, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2004
Materias:
Clinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364792/
https://www.ncbi.nlm.nih.gov/pubmed/15292944
http://dx.doi.org/10.1038/sj.bjc.6601971
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author Ficorella, C
Morelli, M F
Ricevuto, E
Cannita, K
Porzio, G
Baldi, P Lanfiuti
Cianci, G
Rocco, ZC Di
Natoli, C
Tinari, N
Galitiis, F De
Calista, F
Marchetti, P
author_facet Ficorella, C
Morelli, M F
Ricevuto, E
Cannita, K
Porzio, G
Baldi, P Lanfiuti
Cianci, G
Rocco, ZC Di
Natoli, C
Tinari, N
Galitiis, F De
Calista, F
Marchetti, P
author_sort Ficorella, C
collection PubMed
description A dose-finding study was undertaken to determine the maximum-tolerated dose, and the recommended dose of docetaxel in combination with 12-h timed (22:00–10:00) flat infusion of 5-fluorouracil (5-FU) in metastatic breast cancer patients. This schedule seems to reduce the occurrence of stomatitis of the docetaxel and infusional 5-FU regimen.
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spelling pubmed-23647922009-09-10 Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study Ficorella, C Morelli, M F Ricevuto, E Cannita, K Porzio, G Baldi, P Lanfiuti Cianci, G Rocco, ZC Di Natoli, C Tinari, N Galitiis, F De Calista, F Marchetti, P Br J Cancer Clinical A dose-finding study was undertaken to determine the maximum-tolerated dose, and the recommended dose of docetaxel in combination with 12-h timed (22:00–10:00) flat infusion of 5-fluorouracil (5-FU) in metastatic breast cancer patients. This schedule seems to reduce the occurrence of stomatitis of the docetaxel and infusional 5-FU regimen. Nature Publishing Group 2004-08-16 2004-08-03 /pmc/articles/PMC2364792/ /pubmed/15292944 http://dx.doi.org/10.1038/sj.bjc.6601971 Text en Copyright © 2004 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Clinical
Ficorella, C
Morelli, M F
Ricevuto, E
Cannita, K
Porzio, G
Baldi, P Lanfiuti
Cianci, G
Rocco, ZC Di
Natoli, C
Tinari, N
Galitiis, F De
Calista, F
Marchetti, P
Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study
title Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study
title_full Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study
title_fullStr Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study
title_full_unstemmed Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study
title_short Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study
title_sort timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: a dose-finding study
topic Clinical
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364792/
https://www.ncbi.nlm.nih.gov/pubmed/15292944
http://dx.doi.org/10.1038/sj.bjc.6601971
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