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Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma
The WWOX (WW-domain containing oxidoreductase) is a candidate tumour suppressor gene spanning the same chromosome region, 16q23, as the second most common fragile site (FS), FRA16D. Deletions detected by comparative genomic hybridisation (CGH) and loss of heterozygosity at microsatellite markers on...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364795/ https://www.ncbi.nlm.nih.gov/pubmed/15266310 http://dx.doi.org/10.1038/sj.bjc.6602023 |