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Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma

The WWOX (WW-domain containing oxidoreductase) is a candidate tumour suppressor gene spanning the same chromosome region, 16q23, as the second most common fragile site (FS), FRA16D. Deletions detected by comparative genomic hybridisation (CGH) and loss of heterozygosity at microsatellite markers on...

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Detalles Bibliográficos
Autores principales:	Park, S-W, Ludes-Meyers, J, Zimonjic, D B, Durkin, M E, Popescu, N C, Aldaz, C M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2004
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364795/ https://www.ncbi.nlm.nih.gov/pubmed/15266310 http://dx.doi.org/10.1038/sj.bjc.6602023

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