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Degradation of Anthracycline Antitumor Compounds Catalysed by Metal Ions
The influence of some metal ions on the degradation of anthracyclines was examined. One of the degradation products is the 7,8-dehydro-9,10-desacetyldoxorubicinone, D* (¥), usually formed by hydrolysis at slightly basic pH. D* is a lipophilic compound with no cytostatic properties. Its formation cou...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364892/ https://www.ncbi.nlm.nih.gov/pubmed/18476230 http://dx.doi.org/10.1155/MBD.1994.183 |