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Analysis of Multidrug Transporter in Living Cells. Inhibition of P-glycoprotein-mediated Efflux of Anthracyclines by Ionophores

One of the major obstacles of chemotherapy is that, after repeated treatments, cellular resistance to the drug appears. The problem is that the tumor cells become resistant not only to the drugs which have been used during the treatment but also to other drugs which are structurally and functionally...

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Detalles Bibliográficos
Autores principales: Borrel, Marie-Nicole, Pereira, Elene, Fiallo, Marina, Garnier-Suillerot, Arlette
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364894/
https://www.ncbi.nlm.nih.gov/pubmed/18476229
http://dx.doi.org/10.1155/MBD.1994.175