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Redox Chemistry and [Au(CN)(2)(-)] in the Formation of Gold Metabolites

The role of hypochlorite ion, which can be generated by the enzyme myleoperoxidase, in the biochemistry of gold(I) anti-arthritic drugs was investigated. Sodium hypochlorite (OCl(−)) directly and rapidly oxidizes AuSTm, Au(CN)(2)(-), AuSTg (gold thioglucose) and auranofin (Et(3)PAuSATg). The resulti...

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Detalles Bibliográficos
Autores principales:	Shaw III, G. Frank, Schraa, Sabine, Gleichmann, Ernst, Grover, Yash Paul, Dunemann, Lothar, Jagarlamudi, Annapurna
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1994
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364928/ https://www.ncbi.nlm.nih.gov/pubmed/18476255 http://dx.doi.org/10.1155/MBD.1994.351

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