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The Antirheumatic Drug Gold, a Coin With Two Faces: AU(I) and AU(III). Desired and Undesired Effects on the Immune System

Three new findings are reviewed that help to understand the mechanisms of action of antirheumatic Au(I) drugs, such as disodium aurothiomalate (Na(2)Au(I)TM): (i) We found that Na(2)Au(I)TM selectively inhibits T cell receptor (TCR)-mediated antigen recognition by murine CD(4+) T cell hybridomas spe...

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Detalles Bibliográficos
Autores principales: Takahashi, Kazuo, Griem, Peter, Goebel, Carsten, Gonzalez, Jose, Gleichmann, Ernst
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364929/
https://www.ncbi.nlm.nih.gov/pubmed/18476265
http://dx.doi.org/10.1155/MBD.1994.483

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