Complexes With Biologically Active Ligands. Part 4. Coordination Compounds of Chlorothiazide With Transition Metal Ions Behave as Strong Carbonic Anhydrase Inhibitors

Complexes of the diuretic benzothiadiazine derivative chlorothiazide (6-chloro-7-sulfamoyl- 1,2,4-benzothiadiazine-1,1-dioxide) with V(IV); Fe(II); Co(II); Ni(II); Cu(II), Ag(I) and U(VI) were prepared and characterized by elemental analysis, spectroscopic, thermogravimetric, magnetic and conductime...

Descripción completa

Detalles Bibliográficos
Autor principal: Supuran, Claudiu T.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1996
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365006/
https://www.ncbi.nlm.nih.gov/pubmed/18472800
http://dx.doi.org/10.1155/MBD.1996.79
_version_ 1782154063950905344
author Supuran, Claudiu T.
author_facet Supuran, Claudiu T.
author_sort Supuran, Claudiu T.
collection PubMed
description Complexes of the diuretic benzothiadiazine derivative chlorothiazide (6-chloro-7-sulfamoyl- 1,2,4-benzothiadiazine-1,1-dioxide) with V(IV); Fe(II); Co(II); Ni(II); Cu(II), Ag(I) and U(VI) were prepared and characterized by elemental analysis, spectroscopic, thermogravimetric, magnetic and conductimetric measurements. The complexes behave as effective inhibitors for two isozymes (I and II) of carbonic anhydrase (CA).
format Text
id pubmed-2365006
institution National Center for Biotechnology Information
language English
publishDate 1996
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-23650062008-05-12 Complexes With Biologically Active Ligands. Part 4. Coordination Compounds of Chlorothiazide With Transition Metal Ions Behave as Strong Carbonic Anhydrase Inhibitors Supuran, Claudiu T. Met Based Drugs Research Article Complexes of the diuretic benzothiadiazine derivative chlorothiazide (6-chloro-7-sulfamoyl- 1,2,4-benzothiadiazine-1,1-dioxide) with V(IV); Fe(II); Co(II); Ni(II); Cu(II), Ag(I) and U(VI) were prepared and characterized by elemental analysis, spectroscopic, thermogravimetric, magnetic and conductimetric measurements. The complexes behave as effective inhibitors for two isozymes (I and II) of carbonic anhydrase (CA). Hindawi Publishing Corporation 1996 /pmc/articles/PMC2365006/ /pubmed/18472800 http://dx.doi.org/10.1155/MBD.1996.79 Text en Copyright © 1996 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Supuran, Claudiu T.
Complexes With Biologically Active Ligands. Part 4. Coordination Compounds of Chlorothiazide With Transition Metal Ions Behave as Strong Carbonic Anhydrase Inhibitors
title Complexes With Biologically Active Ligands. Part 4. Coordination Compounds of Chlorothiazide With Transition Metal Ions Behave as Strong Carbonic Anhydrase Inhibitors
title_full Complexes With Biologically Active Ligands. Part 4. Coordination Compounds of Chlorothiazide With Transition Metal Ions Behave as Strong Carbonic Anhydrase Inhibitors
title_fullStr Complexes With Biologically Active Ligands. Part 4. Coordination Compounds of Chlorothiazide With Transition Metal Ions Behave as Strong Carbonic Anhydrase Inhibitors
title_full_unstemmed Complexes With Biologically Active Ligands. Part 4. Coordination Compounds of Chlorothiazide With Transition Metal Ions Behave as Strong Carbonic Anhydrase Inhibitors
title_short Complexes With Biologically Active Ligands. Part 4. Coordination Compounds of Chlorothiazide With Transition Metal Ions Behave as Strong Carbonic Anhydrase Inhibitors
title_sort complexes with biologically active ligands. part 4. coordination compounds of chlorothiazide with transition metal ions behave as strong carbonic anhydrase inhibitors
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365006/
https://www.ncbi.nlm.nih.gov/pubmed/18472800
http://dx.doi.org/10.1155/MBD.1996.79
work_keys_str_mv AT supuranclaudiut complexeswithbiologicallyactiveligandspart4coordinationcompoundsofchlorothiazidewithtransitionmetalionsbehaveasstrongcarbonicanhydraseinhibitors

Ejemplares similares