Cargando…
Complexes With Biologically Active Ligands. Part 6(1) Ni(II) Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides as Inhibitors of the Zinc Enzyme Carbonic Anhydrase
Ternary Ni(II) complexes of hydrazine and eight heterocyclic sulfonamides possessing carbonic anhydrase (CA) inhibitory properties, were prepared and characterized by elemental analysis, spectroscopic, magnetic, thermogravimetric, and conductimetric measurements. The complexes behave as strong inhib...
Autores principales: | , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1996
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365015/ https://www.ncbi.nlm.nih.gov/pubmed/18472809 http://dx.doi.org/10.1155/MBD.1996.143 |
_version_ | 1782154066117263360 |
---|---|
author | Borràs, Joaquin Casanova, Javier Cristea, Teodora Gheorghe, Adriana Scozzafava, Andrea Supuran, Claudiu T. Tudor, Violeta |
author_facet | Borràs, Joaquin Casanova, Javier Cristea, Teodora Gheorghe, Adriana Scozzafava, Andrea Supuran, Claudiu T. Tudor, Violeta |
author_sort | Borràs, Joaquin |
collection | PubMed |
description | Ternary Ni(II) complexes of hydrazine and eight heterocyclic sulfonamides possessing carbonic anhydrase (CA) inhibitory properties, were prepared and characterized by elemental analysis, spectroscopic, magnetic, thermogravimetric, and conductimetric measurements. The complexes behave as strong inhibitors for two isozymes (I and II) of carbonic anhydrase. |
format | Text |
id | pubmed-2365015 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1996 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-23650152008-05-12 Complexes With Biologically Active Ligands. Part 6(1) Ni(II) Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides as Inhibitors of the Zinc Enzyme Carbonic Anhydrase Borràs, Joaquin Casanova, Javier Cristea, Teodora Gheorghe, Adriana Scozzafava, Andrea Supuran, Claudiu T. Tudor, Violeta Met Based Drugs Research Article Ternary Ni(II) complexes of hydrazine and eight heterocyclic sulfonamides possessing carbonic anhydrase (CA) inhibitory properties, were prepared and characterized by elemental analysis, spectroscopic, magnetic, thermogravimetric, and conductimetric measurements. The complexes behave as strong inhibitors for two isozymes (I and II) of carbonic anhydrase. Hindawi Publishing Corporation 1996 /pmc/articles/PMC2365015/ /pubmed/18472809 http://dx.doi.org/10.1155/MBD.1996.143 Text en Copyright © 1996 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Borràs, Joaquin Casanova, Javier Cristea, Teodora Gheorghe, Adriana Scozzafava, Andrea Supuran, Claudiu T. Tudor, Violeta Complexes With Biologically Active Ligands. Part 6(1) Ni(II) Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides as Inhibitors of the Zinc Enzyme Carbonic Anhydrase |
title | Complexes With Biologically Active Ligands. Part 6(1) Ni(II)
Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides
as Inhibitors of the Zinc Enzyme Carbonic Anhydrase |
title_full | Complexes With Biologically Active Ligands. Part 6(1) Ni(II)
Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides
as Inhibitors of the Zinc Enzyme Carbonic Anhydrase |
title_fullStr | Complexes With Biologically Active Ligands. Part 6(1) Ni(II)
Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides
as Inhibitors of the Zinc Enzyme Carbonic Anhydrase |
title_full_unstemmed | Complexes With Biologically Active Ligands. Part 6(1) Ni(II)
Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides
as Inhibitors of the Zinc Enzyme Carbonic Anhydrase |
title_short | Complexes With Biologically Active Ligands. Part 6(1) Ni(II)
Coordination Compounds of Hydrazine and Heterocyclic Sulfonamides
as Inhibitors of the Zinc Enzyme Carbonic Anhydrase |
title_sort | complexes with biologically active ligands. part 6(1) ni(ii)
coordination compounds of hydrazine and heterocyclic sulfonamides
as inhibitors of the zinc enzyme carbonic anhydrase |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365015/ https://www.ncbi.nlm.nih.gov/pubmed/18472809 http://dx.doi.org/10.1155/MBD.1996.143 |
work_keys_str_mv | AT borrasjoaquin complexeswithbiologicallyactiveligandspart61niiicoordinationcompoundsofhydrazineandheterocyclicsulfonamidesasinhibitorsofthezincenzymecarbonicanhydrase AT casanovajavier complexeswithbiologicallyactiveligandspart61niiicoordinationcompoundsofhydrazineandheterocyclicsulfonamidesasinhibitorsofthezincenzymecarbonicanhydrase AT cristeateodora complexeswithbiologicallyactiveligandspart61niiicoordinationcompoundsofhydrazineandheterocyclicsulfonamidesasinhibitorsofthezincenzymecarbonicanhydrase AT gheorgheadriana complexeswithbiologicallyactiveligandspart61niiicoordinationcompoundsofhydrazineandheterocyclicsulfonamidesasinhibitorsofthezincenzymecarbonicanhydrase AT scozzafavaandrea complexeswithbiologicallyactiveligandspart61niiicoordinationcompoundsofhydrazineandheterocyclicsulfonamidesasinhibitorsofthezincenzymecarbonicanhydrase AT supuranclaudiut complexeswithbiologicallyactiveligandspart61niiicoordinationcompoundsofhydrazineandheterocyclicsulfonamidesasinhibitorsofthezincenzymecarbonicanhydrase AT tudorvioleta complexeswithbiologicallyactiveligandspart61niiicoordinationcompoundsofhydrazineandheterocyclicsulfonamidesasinhibitorsofthezincenzymecarbonicanhydrase |