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Cytotoxic Action of Carboxyborane Heterocyclic Amine Adducts

The heterocyclic carboxyborane amines were found to be potent cytotoxic agents in the murine L1210 lymphoid leukemia and human HeLa suspended carcinoma cells. These agents were observed to inhibit HeLa DNA topoisomerase II activity ~ 200 μM and L1210 topoisomerase II activity ≥ 100 μM. These agents...

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Detalles Bibliográficos
Autores principales:	Miller, Merrill C., Sood, Anup, Spielvogel, Bernard F., Bastow, Ken, Hall, Iris H.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1997
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365064/ https://www.ncbi.nlm.nih.gov/pubmed/18475792 http://dx.doi.org/10.1155/MBD.1997.229

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