Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct

Antitumor activity of the adduct between Carboplatin and α-cyclodextrin has been tested against Sarcoma 180 (S(180)) and Ehrlich ascites carcinoma (EAC) murine tumors. The preliminary toxicity has also been evaluated by histological examinations of the treated animals. The results show the adduct ha...

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Autores principales: Liu, Weiping, Xiong, Huizhou, Yang, Yikun, Li, Ling, Shen, Zhiqiang, Chen, Zhihe
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365085/
https://www.ncbi.nlm.nih.gov/pubmed/18475810
http://dx.doi.org/10.1155/MBD.1997.305
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author Liu, Weiping
Xiong, Huizhou
Yang, Yikun
Li, Ling
Shen, Zhiqiang
Chen, Zhihe
author_facet Liu, Weiping
Xiong, Huizhou
Yang, Yikun
Li, Ling
Shen, Zhiqiang
Chen, Zhihe
author_sort Liu, Weiping
collection PubMed
description Antitumor activity of the adduct between Carboplatin and α-cyclodextrin has been tested against Sarcoma 180 (S(180)) and Ehrlich ascites carcinoma (EAC) murine tumors. The preliminary toxicity has also been evaluated by histological examinations of the treated animals. The results show the adduct has less antitumor efficacy than and similar toxicity to Carboplatin.
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spelling pubmed-23650852008-05-12 Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct Liu, Weiping Xiong, Huizhou Yang, Yikun Li, Ling Shen, Zhiqiang Chen, Zhihe Met Based Drugs Research Article Antitumor activity of the adduct between Carboplatin and α-cyclodextrin has been tested against Sarcoma 180 (S(180)) and Ehrlich ascites carcinoma (EAC) murine tumors. The preliminary toxicity has also been evaluated by histological examinations of the treated animals. The results show the adduct has less antitumor efficacy than and similar toxicity to Carboplatin. Hindawi Publishing Corporation 1997 /pmc/articles/PMC2365085/ /pubmed/18475810 http://dx.doi.org/10.1155/MBD.1997.305 Text en Copyright © 1997 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Liu, Weiping
Xiong, Huizhou
Yang, Yikun
Li, Ling
Shen, Zhiqiang
Chen, Zhihe
Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct
title Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct
title_full Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct
title_fullStr Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct
title_full_unstemmed Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct
title_short Antitumor Activity of the Carboplatin-α-Cyclodextrin Adduct
title_sort antitumor activity of the carboplatin-α-cyclodextrin adduct
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365085/
https://www.ncbi.nlm.nih.gov/pubmed/18475810
http://dx.doi.org/10.1155/MBD.1997.305
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AT liling antitumoractivityofthecarboplatinacyclodextrinadduct
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