Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity

The coordinatively unsaturated copper (II) complexes of 1,3-bis(2'-pyridyl)-1,2-diaza-2- butene with different ancillary anions were synthesized which can bind to copper centers of tyrosinase enzyme. The compounds were found to exhibit inhibitory activities against mushroom tyrosinase and the n...

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Autores principales: Bendre, Ratnamala, Murugkar, Anupa, Padhye, Subhash, Kulkarni, Pallavi, Karve, Meena
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365098/
https://www.ncbi.nlm.nih.gov/pubmed/18475824
http://dx.doi.org/10.1155/MBD.1998.59
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author Bendre, Ratnamala
Murugkar, Anupa
Padhye, Subhash
Kulkarni, Pallavi
Karve, Meena
author_facet Bendre, Ratnamala
Murugkar, Anupa
Padhye, Subhash
Kulkarni, Pallavi
Karve, Meena
author_sort Bendre, Ratnamala
collection PubMed
description The coordinatively unsaturated copper (II) complexes of 1,3-bis(2'-pyridyl)-1,2-diaza-2- butene with different ancillary anions were synthesized which can bind to copper centers of tyrosinase enzyme. The compounds were found to exhibit inhibitory activities against mushroom tyrosinase and the nature and extent of inhibition is modulated according to the type of ancillary anions.
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spelling pubmed-23650982008-05-12 Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity Bendre, Ratnamala Murugkar, Anupa Padhye, Subhash Kulkarni, Pallavi Karve, Meena Met Based Drugs Research Article The coordinatively unsaturated copper (II) complexes of 1,3-bis(2'-pyridyl)-1,2-diaza-2- butene with different ancillary anions were synthesized which can bind to copper centers of tyrosinase enzyme. The compounds were found to exhibit inhibitory activities against mushroom tyrosinase and the nature and extent of inhibition is modulated according to the type of ancillary anions. Hindawi Publishing Corporation 1998 /pmc/articles/PMC2365098/ /pubmed/18475824 http://dx.doi.org/10.1155/MBD.1998.59 Text en Copyright © 1998 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Bendre, Ratnamala
Murugkar, Anupa
Padhye, Subhash
Kulkarni, Pallavi
Karve, Meena
Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity
title Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity
title_full Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity
title_fullStr Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity
title_full_unstemmed Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity
title_short Synthesis and Characterization of Coordinatively Unsaturated Copper (II) Complexes of 1,3-Bis(2'-Pyridyl)-1,2-Diaza-2-Butene and Their Antityrosinase Activity
title_sort synthesis and characterization of coordinatively unsaturated copper (ii) complexes of 1,3-bis(2'-pyridyl)-1,2-diaza-2-butene and their antityrosinase activity
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365098/
https://www.ncbi.nlm.nih.gov/pubmed/18475824
http://dx.doi.org/10.1155/MBD.1998.59
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