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Antitumour Metallocenes: Effect of DMSO on the Stability of Cp(2)TiX(2) and Implications for Anticancer Activity

The rate of hydrolysis of the aromatic rings of Cp(2)TiX(2) [X = CI 1, O(2)CCCl(3) 8 and O(2)CCH(2)NH(3)Cl 13], in aqueous solutions, 10%DMSO and 100% DMSO have been studied by (1)H NMR spectroscopy. Rapid hydrolysis of both the carboxylate and cyclopentadienyl ligands in Cp(2)TiX(2)[X = O(2)CCCl(3)...

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Detalles Bibliográficos
Autores principales: Mokdsi, George, Harding, Margaret M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365120/
https://www.ncbi.nlm.nih.gov/pubmed/18475845
http://dx.doi.org/10.1155/MBD.1998.207