Distribution of Copper in Rats Submitted to Treatment With Copper Aspirinate

The distribution of copper in Sprague – Dawley rats following a three month oral administration of 0,10 or 50mg/kg copper aspirinate has been investigated. Metal content was determined by ICP – AES in blood, brain, kidney, liver, lung, spleen, and dejection. The results show that treatment with copp...

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Detalles Bibliográficos
Autores principales: Liu, Weiping, Yang, Yikun, Xiong, Huizhou, Lu, Ying, Yang, Rong
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1998
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365142/
https://www.ncbi.nlm.nih.gov/pubmed/18475869
http://dx.doi.org/10.1155/MBD.1998.333
Descripción
Sumario:The distribution of copper in Sprague – Dawley rats following a three month oral administration of 0,10 or 50mg/kg copper aspirinate has been investigated. Metal content was determined by ICP – AES in blood, brain, kidney, liver, lung, spleen, and dejection. The results show that treatment with copper aspirinate did not cause accumulation of copper in rats and excess ingested copper was excreted through feces.

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