Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities

Iron(II) and iron(III) complexes of 3,5-di-tert-butyl-o-benzoquinonemonooxime were synthesized and characterized by spectroscopic and electrochemical studies. Their ability to cleave DNA has been investigated under aerobic conditions at room temperature and in the presence and absence of H(2) O(2)....

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Detalles Bibliográficos
Autores principales: Murugkar, Anupa, Padhye, Subhash, Deobagkar, Deepti
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1999
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365165/
https://www.ncbi.nlm.nih.gov/pubmed/18475885
http://dx.doi.org/10.1155/MBD.1999.81
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author Murugkar, Anupa
Padhye, Subhash
Deobagkar, Deepti
author_facet Murugkar, Anupa
Padhye, Subhash
Deobagkar, Deepti
author_sort Murugkar, Anupa
collection PubMed
description Iron(II) and iron(III) complexes of 3,5-di-tert-butyl-o-benzoquinonemonooxime were synthesized and characterized by spectroscopic and electrochemical studies. Their ability to cleave DNA has been investigated under aerobic conditions at room temperature and in the presence and absence of H(2) O(2). The plasmid DNA pBR322 was effectively cleaved by these complexes in a concentration dependant manner.
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spelling pubmed-23651652008-05-12 Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities Murugkar, Anupa Padhye, Subhash Deobagkar, Deepti Met Based Drugs Research Article Iron(II) and iron(III) complexes of 3,5-di-tert-butyl-o-benzoquinonemonooxime were synthesized and characterized by spectroscopic and electrochemical studies. Their ability to cleave DNA has been investigated under aerobic conditions at room temperature and in the presence and absence of H(2) O(2). The plasmid DNA pBR322 was effectively cleaved by these complexes in a concentration dependant manner. Hindawi Publishing Corporation 1999 /pmc/articles/PMC2365165/ /pubmed/18475885 http://dx.doi.org/10.1155/MBD.1999.81 Text en Copyright © 1999 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Murugkar, Anupa
Padhye, Subhash
Deobagkar, Deepti
Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities
title Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities
title_full Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities
title_fullStr Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities
title_full_unstemmed Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities
title_short Synthesis, Spectroscopy and Electrochemistry of Fe(II) and Fe(III) Quinonemonooxime Complexes and Their DNA Cleaving Activities
title_sort synthesis, spectroscopy and electrochemistry of fe(ii) and fe(iii) quinonemonooxime complexes and their dna cleaving activities
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365165/
https://www.ncbi.nlm.nih.gov/pubmed/18475885
http://dx.doi.org/10.1155/MBD.1999.81
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