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A Screening Strategy for Metal Antitumor Agents as Exemplified by Gold(III) Complexes
The use of a screening strategy based on human tumor cell lines, which are also tumorigenic in immune-deprived mice, is described. Activity against the human tumor cells in vitro and in vivo, is complemented with studies on the mechanism of action. This aporoach is demonstrated using 2-[(dimethylami...
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| Formato: | Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365177/ https://www.ncbi.nlm.nih.gov/pubmed/18475904 http://dx.doi.org/10.1155/MBD.1999.291 |