Cargando…

Cellular Uptake, DNA Binding and Apoptosis Induction of Cytotoxic Trans-[PtCl(2)(N,N-dimethylamine)(Isopropylamine)] in A2780cisR Ovarian Tumor Cells

Trans-[PtCl(2)(N,N-dimethylamine)(isopropylamine)] is a novel trans-platinum compound that shows cytotoxic activity in several cisplatin resistant cell lines. The aim of this paper was to analyse, by means of molecular cell biology techniques and total reflection X-ray fluorescence (TXRF), the cytot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pérez, José M., Montero, Eva I., Quiroga, Adoración G., Fuertes, Miguel A, Alonso, Carlos, Navarro-Ranninger, Carmen
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2001
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365251/ https://www.ncbi.nlm.nih.gov/pubmed/18475973 http://dx.doi.org/10.1155/MBD.2001.29

Ejemplares similares

Formation, Characterization, and Bonding of cis- and trans-[PtCl(2){Te(CH(2))(6)}(2)], cis-trans-[Pt(3)Cl(6){Te(CH(2))(6)}(4)], and cis-trans-[Pt(4)Cl(8){Te(CH(2))(6)}(4)]: Experimental and DFT Study †
por: Rodewald, Marko, et al.
Publicado: (2023)

Overcoming multidrug resistance by activating unfolded protein response of the endoplasmic reticulum in cisplatin-resistant A2780/CisR ovarian cancer cells
por: Jung, Euitaek, et al.
Publicado: (2020)

In Vitro and in vivo Evaluation of Electrochemotherapy with trans-platinum Analogue trans-[PtCl(2)(3-Hmpy)(2)]
por: Kranjc, Simona, et al.
Publicado: (2017)

Caenorhabditis elegans cisRED: a catalogue of conserved genomic elements
por: Sleumer, Monica C., et al.
Publicado: (2009)

Low-Dimensional Architectures in Isomeric cis-PtCl(2){Ph(2)PCH(2)N(Ar)CH(2)PPh(2)} Complexes Using Regioselective-N(Aryl)-Group Manipulation
por: De’Ath, Peter, et al.
Publicado: (2021)

cisRED: a database system for genome-scale computational discovery of regulatory elements
por: Robertson, G., et al.
Publicado: (2006)

[N,N-Bis(diphenylphosphino)isopropylamine]dibromidonickel(II)
por: Hapke, Marko, et al.
Publicado: (2009)

A 5′-Phosphodiester Group Attached to Deoxyguanosine does not Accelerate the Hydrolysis of cis-[PtCl(NH(3))(2)(dGuo)](3)
por: Weber, Tiphaine, et al.
Publicado: (1999)

Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of Antitumor trans-[PtCl(2)(NH(3))(thiazole)]
por: Marini, Victoria, et al.
Publicado: (2005)

Screening and Preliminary Biochemical and Biological Studies of [RuCl(p-cymene)(N,N-bis(diphenylphosphino)-isopropylamine)][BF(4)] in Breast Cancer Models
por: Corrales Sánchez, Veronica, et al.
Publicado: (2019)

The mode of action of cis dichloro-bis (isopropylamine) trans dihydroxy platinum IV (CHIP) studied by the analysis of chromosome aberration production.
por: Bocian, E., et al.
Publicado: (1983)

Sister chromatid exchanges induced by two radiosensitizing platinum compounds (cis-dichloro-bis isopropylamine trans dihydroxy platinum IV (CHIP) and cis platinum metronidazole2Cl2(FLAP] in CHO cells in vitro.
por: Bocian, E., et al.
Publicado: (1983)

A Spectroscopic Study on PtCl(4)((2−)) Binding to Rabbit Skeletal Muscle G-Actin
por: Zou , Juan, et al.
Publicado: (1995)

Identification of Binding Mode of a Platinum (II) Complex, PtCl(2)(DIP), and Calf Thymus DNA
por: Shahabadi, Nahid, et al.
Publicado: (2011)

Molecular Recognition of Metal Complexes by DNA: A Comparative Study of the Interactions of the Parent Complexes [PtCl(TERPY)]Cl and [AuCl(TERPY)]Cl (2) with Double Stranded DNA
por: Messori, Luigi, et al.
Publicado: (2005)

Structural Characterization of Cis– and Trans–Pt(NH(3))(2)Cl(2) Conjugations with Chitosan Nanoparticles
por: Chanphai, Penparapa, et al.
Publicado: (2022)

Synthesis of no-carrier-added [(188, 189, 191)Pt]cisplatin from a cyclotron produced (188, 189, 191)PtCl(4)(2−) complex
por: Obata, Honoka, et al.
Publicado: (2021)

Microsecond time-resolved energy-dispersive EXAFS measurement and its application to film the thermolysis of (NH(4))(2)[PtCl(6)]
por: Kong, Qingyu, et al.
Publicado: (2012)

Rich Collection of n-Propylamine and Isopropylamine Conformers: Rotational Fingerprints and State-of-the-Art Quantum Chemical Investigation
por: Melosso, Mattia, et al.
Publicado: (2020)

(2-Decanamidoethyl)dimethylamine N-oxide
por: Lewińska, Agnieszka
Publicado: (2010)

New Findings in the Signaling Pathways of cis and trans Platinum Iodido Complexes’ Interaction with DNA of Cancer Cells
por: Quiroga, Adoración G., et al.
Publicado: (2019)

Ternary Complexes of cis-(NH(3))(2)PtCl(2) (cis-DDP) With Guanosine (guo), Cytidine (cyd) and the Aminoacids Glycine (gly), L-Alanine (ala), L-2-Aminobutyric Acid (2-aba), L-Norvaline (nval) and L-Norleucine (nleu)
por: Katsarou, Erasmia, et al.
Publicado: (1997)

Ternary Complexes of cis-(NH(3))(2)PtCl(2) (cis-DDP) With Guanosine (guo), Cytidine (cyd) and the Aminoacids Glycine (gly), L-Alanine (ala), L-2-Aminobutyric Acid (2-aba), L-Norvaline (nval) and L-Norleucine (nleu)
por: Katsarou, Erasmia, et al.
Publicado: (1997)

cis/trans-[Pt(C(∧)N)(C≡CR)(CNBu(t))] Isomers: Synthesis, Photophysical, DFT Studies, and Chemosensory Behavior
por: Martínez-Junquera, Mónica, et al.
Publicado: (2023)

Lipophilic Fe(III)-Complex with Potent Broad-Spectrum Anticancer Activity and Ability to Overcome Pt Resistance in A2780cis Cancer Cells
por: Abeydeera, Nalin, et al.
Publicado: (2023)

Dimethylamine Borane Neurotoxicity
por: Huang, Chin-Chang, et al.
Publicado: (2006)

Dichlorido{N-[2-(diphenylphosphanyl)benzylidene]isopropylamine-κ(2) N,P}palladium(II) dimethyl sulfoxide monosolvate
por: Chiririwa, Haleden, et al.
Publicado: (2011)

Association of Trimethylamine, Trimethylamine N-oxide, and Dimethylamine with Cardiovascular Risk in Children with Chronic Kidney Disease
por: Hsu, Chien-Ning, et al.
Publicado: (2020)

Dimethylamine Borane: Tsan and Hung Respond
por: Tsan, Yu-Tse, et al.
Publicado: (2006)

Dibromidotris(dimethylamine)magnesium(II)
por: Vitze, Hannes, et al.
Publicado: (2009)

Editorial: PTCL from genes to therapy
por: Janikova, Andrea
Publicado: (2022)

Interaction of Cis- and Trans-RuCl (2)(DMSO)(4) With Human Serum Albumin
por: Trynda-Lemiesz, Lilianna, et al.
Publicado: (2000)

Evaluation of genetic damage induced by glyphosate isopropylamine salt using Tradescantia bioassays
por: Alvarez-Moya, Carlos, et al.
Publicado: (2011)

Comparison of the in vivo and in vitro genotoxicity of glyphosate isopropylamine salt in three different organisms
por: Alvarez-Moya, Carlos, et al.
Publicado: (2014)

Crystal structure of tris(dimethylamido-κN)bis(dimethylamine-κN)zirconium(IV) iodide
por: Clark, Wesley D., et al.
Publicado: (2016)

Synthesis, Characterization and Antitumor Activity of cis-bis(acylthioureato) platinum(II) Complexes, cis-[PtL(2)] [HL(1)=N,N-Diphenyl-N'-Benzoylthiourea or HL(2)=N,N-diphenyl-N'-(p-nitrobenzoyl)thiourea]
por: Hernández, Wilfredo, et al.
Publicado: (2003)

Case Report: The Clinical Toxicity of Dimethylamine Borane
por: Tsan, Yu-Tse, et al.
Publicado: (2005)

N-{4-[3-(4-Fluorophenyl)pyrido[2,3-b]pyrazin-2-yl]-2-pyridyl}isopropylamine
por: Koch, Pierre, et al.
Publicado: (2009)

Isobutylamine, Isopropylamine, sec-Butylamine, Propylamine, Hexylamine, Pentylamine and 2-Methylbutylamine (Flavoring Substances)
Publicado: (2019)

Role of N-Cadherin cis and trans Interfaces in the Dynamics of Adherens Junctions in Living Cells
por: Bunse, Stefanie, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_etjfd0aii0otk9ts2cspr51pj1