Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex

A square planar copper complex of derivatized NSAID drug (Ketoprofen thiosemicarbazone [3-benzoyl-α-methyl benzene acetic acid thiosemicarbazone]), is characterized by elemental analysis, spectroscopy, electrochemistry and magnetic susceptibility studies which exhibits dose-dependent and enhanced an...

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Detalles Bibliográficos
Autores principales: Saha, Dilip Kumar, Padhye, Shreelekha, Padhye, Subhash
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365256/
https://www.ncbi.nlm.nih.gov/pubmed/18475978
http://dx.doi.org/10.1155/MBD.2001.73
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author Saha, Dilip Kumar
Padhye, Shreelekha
Padhye, Subhash
author_facet Saha, Dilip Kumar
Padhye, Shreelekha
Padhye, Subhash
author_sort Saha, Dilip Kumar
collection PubMed
description A square planar copper complex of derivatized NSAID drug (Ketoprofen thiosemicarbazone [3-benzoyl-α-methyl benzene acetic acid thiosemicarbazone]), is characterized by elemental analysis, spectroscopy, electrochemistry and magnetic susceptibility studies which exhibits dose-dependent and enhanced antiproliferative effects on human breast cancer cell line T47D rich in progesterone receptors.
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spelling pubmed-23652562008-05-12 Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex Saha, Dilip Kumar Padhye, Shreelekha Padhye, Subhash Met Based Drugs Research Article A square planar copper complex of derivatized NSAID drug (Ketoprofen thiosemicarbazone [3-benzoyl-α-methyl benzene acetic acid thiosemicarbazone]), is characterized by elemental analysis, spectroscopy, electrochemistry and magnetic susceptibility studies which exhibits dose-dependent and enhanced antiproliferative effects on human breast cancer cell line T47D rich in progesterone receptors. Hindawi Publishing Corporation 2001 /pmc/articles/PMC2365256/ /pubmed/18475978 http://dx.doi.org/10.1155/MBD.2001.73 Text en Copyright © 2001 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Saha, Dilip Kumar
Padhye, Shreelekha
Padhye, Subhash
Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex
title Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex
title_full Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex
title_fullStr Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex
title_full_unstemmed Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex
title_short Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex
title_sort targeting estrogen receptor sites in human breast cancer cell line t47d with copper conjugates of nonsteriodal anti-inflammatory drug derivatives: antiproliferative activity of ketoprofen derivative and its copper complex
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365256/
https://www.ncbi.nlm.nih.gov/pubmed/18475978
http://dx.doi.org/10.1155/MBD.2001.73
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AT padhyeshreelekha targetingestrogenreceptorsitesinhumanbreastcancercelllinet47dwithcopperconjugatesofnonsteriodalantiinflammatorydrugderivativesantiproliferativeactivityofketoprofenderivativeanditscoppercomplex
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