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Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands

The antibacterial and antifungal activity of zinc(II) carboxylates with composition Zn(RCOO)(2)•nH(2)O(R =H-, CH(3)(-), CH(3)CH(2)CH(2)(-), (CH(3))(2)CH-, XCH(2)(-), X=Cl, Br, I, n=0 or 2), [ZnX(2)(Nia(+)CH(2)COO(-))(2)](Nia=nicotinamide, X=Cl, Br, I) and [Zn(XCH(2)COO)(2)(Caf)(2)]•2H(2)O (Car=caffe...

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Detalles Bibliográficos
Autores principales: Zelenák, V., Györyová, K., Mlynarcík, D.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365280/
https://www.ncbi.nlm.nih.gov/pubmed/18476005
http://dx.doi.org/10.1155/MBD.2002.269
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author Zelenák, V.
Györyová, K.
Mlynarcík, D.
author_facet Zelenák, V.
Györyová, K.
Mlynarcík, D.
author_sort Zelenák, V.
collection PubMed
description The antibacterial and antifungal activity of zinc(II) carboxylates with composition Zn(RCOO)(2)•nH(2)O(R =H-, CH(3)(-), CH(3)CH(2)CH(2)(-), (CH(3))(2)CH-, XCH(2)(-), X=Cl, Br, I, n=0 or 2), [ZnX(2)(Nia(+)CH(2)COO(-))(2)](Nia=nicotinamide, X=Cl, Br, I) and [Zn(XCH(2)COO)(2)(Caf)(2)]•2H(2)O (Car=caffeine, X=Cl, Br) is studied against bacterial strains Staphylococcus aureus, Escherichia coli and yeast Candida albicans. The structural types are assigned to the prepared compounds and the influence of (i) carboxylate chain length, (ii) substitution of hydrogen atom of carboxylate by halogen and (iii) presence of N-donor organic ligands on the biological activity is discussed.
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spelling pubmed-23652802008-05-12 Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands Zelenák, V. Györyová, K. Mlynarcík, D. Met Based Drugs Research Article The antibacterial and antifungal activity of zinc(II) carboxylates with composition Zn(RCOO)(2)•nH(2)O(R =H-, CH(3)(-), CH(3)CH(2)CH(2)(-), (CH(3))(2)CH-, XCH(2)(-), X=Cl, Br, I, n=0 or 2), [ZnX(2)(Nia(+)CH(2)COO(-))(2)](Nia=nicotinamide, X=Cl, Br, I) and [Zn(XCH(2)COO)(2)(Caf)(2)]•2H(2)O (Car=caffeine, X=Cl, Br) is studied against bacterial strains Staphylococcus aureus, Escherichia coli and yeast Candida albicans. The structural types are assigned to the prepared compounds and the influence of (i) carboxylate chain length, (ii) substitution of hydrogen atom of carboxylate by halogen and (iii) presence of N-donor organic ligands on the biological activity is discussed. Hindawi Publishing Corporation 2002 /pmc/articles/PMC2365280/ /pubmed/18476005 http://dx.doi.org/10.1155/MBD.2002.269 Text en Copyright © 2002 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zelenák, V.
Györyová, K.
Mlynarcík, D.
Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands
title Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands
title_full Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands
title_fullStr Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands
title_full_unstemmed Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands
title_short Antibacterial and Antifungal Activity of Zinc(II) Carboxylates With/Without N-Donor Organic Ligands
title_sort antibacterial and antifungal activity of zinc(ii) carboxylates with/without n-donor organic ligands
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365280/
https://www.ncbi.nlm.nih.gov/pubmed/18476005
http://dx.doi.org/10.1155/MBD.2002.269
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