Serum levels of interleukin-6 are not dependent on the kidney function

Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relati...

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Detalles Bibliográficos
Autor principal: Nässberger, L.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1992
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365338/
https://www.ncbi.nlm.nih.gov/pubmed/18475461
http://dx.doi.org/10.1155/S0962935192000309
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author Nässberger, L.
author_facet Nässberger, L.
author_sort Nässberger, L.
collection PubMed
description Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relation was found between serum levels of IL-6 and s-creatinine, r = 0.004. On the other hand, the serum concentration of complement protein factor D and soluble IL-2 receptor showed a good correlation to s-creatinine, r = 0.92 and 0.79, respectively. In conclusion, serum levels of IL-6 are not dependent upon a reduced kidney function.
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spelling pubmed-23653382008-05-12 Serum levels of interleukin-6 are not dependent on the kidney function Nässberger, L. Mediators Inflamm Research Article Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions. We investigated the importance of a deteriorated kidney function upon IL-6 serum concentrations. No relation was found between serum levels of IL-6 and s-creatinine, r = 0.004. On the other hand, the serum concentration of complement protein factor D and soluble IL-2 receptor showed a good correlation to s-creatinine, r = 0.92 and 0.79, respectively. In conclusion, serum levels of IL-6 are not dependent upon a reduced kidney function. Hindawi Publishing Corporation 1992 /pmc/articles/PMC2365338/ /pubmed/18475461 http://dx.doi.org/10.1155/S0962935192000309 Text en Copyright © 1992 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Nässberger, L.
Serum levels of interleukin-6 are not dependent on the kidney function
title Serum levels of interleukin-6 are not dependent on the kidney function
title_full Serum levels of interleukin-6 are not dependent on the kidney function
title_fullStr Serum levels of interleukin-6 are not dependent on the kidney function
title_full_unstemmed Serum levels of interleukin-6 are not dependent on the kidney function
title_short Serum levels of interleukin-6 are not dependent on the kidney function
title_sort serum levels of interleukin-6 are not dependent on the kidney function
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365338/
https://www.ncbi.nlm.nih.gov/pubmed/18475461
http://dx.doi.org/10.1155/S0962935192000309
work_keys_str_mv AT nassbergerl serumlevelsofinterleukin6arenotdependentonthekidneyfunction

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