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Tumour necrosis factor (TNF) and interleukin-1 (IL-1) induce muscle proteolysis through different mechanisms

The purpose of this study was to test the hypothesis that muscle proteolysis induced by TNF or IL-1 is mediated by glucocorticoids. Rats were treated with 300 μg kg(−1) of recombinant human preparations of IL-1α (rIL-1α) or TNFα (rTNFα) divided into three equal intraperitoneal doses given over 16 h....

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Detalles Bibliográficos
Autores principales:	Zamir, Oded, Hasselgren, Per-Olof, Higashiguchi, Takashi, Frederick, Janice A., Fischer, Josef E.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1992
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365344/ https://www.ncbi.nlm.nih.gov/pubmed/18475468 http://dx.doi.org/10.1155/S0962935192000371

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