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IL-1β and IL-6 modulate apolipoprotein E gene expression in rat hepatocyte primary culture

Incubation of rat hepatocytes in primary culture with IL-1β at a concentration of 2.5 units/ml resulted in an increase (+80%) in the amount of apoE mRNA without any effect upon apoE synthesis. IL-6 at a low concentration (10 units/ml) induced a decrease (−35%) in the amount of apoE mRNA, but increas...

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Detalles Bibliográficos
Autores principales:	Ribeiro, Agnes, Mangeney, Marise, Bernard, Isabelle, Chambaz, Jean, Delers, Francisco
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1992
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365358/ https://www.ncbi.nlm.nih.gov/pubmed/18475480 http://dx.doi.org/10.1155/S0962935192000498

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