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Differential regulation of TNF-α and IL-1β production from endotoxin stimulated human monocytes by phosphodiesterase inhibitors

The effect of selective PDE-I (vinpocetine), PDE-III (milrinone, CI-930), PDE-IV (rolipram, nitroquazone), and PDE-V (zaprinast) isozyme inhibitors on TNF-α and IL-1β production from LPS stimulated human monocytes was investigated. The PDE-IV inhibitors caused a concentration dependent inhibition of...

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Detalles Bibliográficos
Autores principales:	Molnar-Kimber, K. L., Yonno, L., Heaslip, R. J., Weichman, B. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1992
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365371/ https://www.ncbi.nlm.nih.gov/pubmed/18475493 http://dx.doi.org/10.1155/S0962935192000620

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