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Heparan sulphate inhibition of cell proliferation induced by TGFβ and PDGF

The effect of glycosaminoglycans (GAGs) on the proliferation of smooth muscle cells (SMC) and fibroblasts was assessed by culturing cells with or without GAGs. Porcine heparan sulphate (HS) inhibited proliferation in a dose dependent manner. At 167 μg/ml of HS this reached 88% and 72% inhibition of...

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Detalles Bibliográficos
Autores principales:	Silber, lan E., Walenga, Jeanine M., Fareed, Jawed, Kovacs, Elizabeth J.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1993
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365412/ https://www.ncbi.nlm.nih.gov/pubmed/18475537 http://dx.doi.org/10.1155/S0962935193000419

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