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Calcium ionophore (A-23187) induced peritoneal eicosanoid biosynthesis: a rapid method to evaluate inhibitors of arachidonic acid metabolism in vivo

The present investigation characterizes calcium ionophore (A-23187) induced peritoneal eicosanoid biosynthesis in the rat. Intraperitoneal injection of A-23187 (20 μg/rat) stimulated marked biosynthesis of 6-keto-PGF(1α) (6-KPA), TxB(2), LTC(4) and LTB(4), with no detectable changes on levels of PGE...

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Detalles Bibliográficos
Autores principales:	Rao, T. S., Currie, J. L., Shaffer, A. F., Isakson, P. C.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1993
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365427/ https://www.ncbi.nlm.nih.gov/pubmed/18475545 http://dx.doi.org/10.1155/S0962935193000493

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