L-carnitine: a partner between immune response and lipid metabolism ?

The authors demonstrated that in vivo administered L-carnitine strongly ameliorated the immune response in both healthy individuals receiving Intralipid and ageing subjects with cardiovascular diseases, as shown by the enhancement of mixed lymphocyte reaction. Notably, in the latter group L-carnitin...

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Autores principales: Famularo, Giuseppe, Tzantzoglou, Sonia, Santini, Gino, Trinchieri, Vito, Moretti, Sonia, Koverech, Aleardo, De Simone, Claudio
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365452/
https://www.ncbi.nlm.nih.gov/pubmed/18475566
http://dx.doi.org/10.1155/S0962935193000729
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author Famularo, Giuseppe
Tzantzoglou, Sonia
Santini, Gino
Trinchieri, Vito
Moretti, Sonia
Koverech, Aleardo
De Simone, Claudio
author_facet Famularo, Giuseppe
Tzantzoglou, Sonia
Santini, Gino
Trinchieri, Vito
Moretti, Sonia
Koverech, Aleardo
De Simone, Claudio
author_sort Famularo, Giuseppe
collection PubMed
description The authors demonstrated that in vivo administered L-carnitine strongly ameliorated the immune response in both healthy individuals receiving Intralipid and ageing subjects with cardiovascular diseases, as shown by the enhancement of mixed lymphocyte reaction. Notably, in the latter group L-carnitine treatment also resulted in a significant reduction of serum levels of both cholesterol and triglycerides. Therefore, the hypothesis is that L-carnitine supplementation could ameliorate both the dysregulated immune response and the abnormal lipid metabolism in several conditions.
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spelling pubmed-23654522008-05-12 L-carnitine: a partner between immune response and lipid metabolism ? Famularo, Giuseppe Tzantzoglou, Sonia Santini, Gino Trinchieri, Vito Moretti, Sonia Koverech, Aleardo De Simone, Claudio Mediators Inflamm Research Article The authors demonstrated that in vivo administered L-carnitine strongly ameliorated the immune response in both healthy individuals receiving Intralipid and ageing subjects with cardiovascular diseases, as shown by the enhancement of mixed lymphocyte reaction. Notably, in the latter group L-carnitine treatment also resulted in a significant reduction of serum levels of both cholesterol and triglycerides. Therefore, the hypothesis is that L-carnitine supplementation could ameliorate both the dysregulated immune response and the abnormal lipid metabolism in several conditions. Hindawi Publishing Corporation 1993 /pmc/articles/PMC2365452/ /pubmed/18475566 http://dx.doi.org/10.1155/S0962935193000729 Text en Copyright © 1993 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Famularo, Giuseppe
Tzantzoglou, Sonia
Santini, Gino
Trinchieri, Vito
Moretti, Sonia
Koverech, Aleardo
De Simone, Claudio
L-carnitine: a partner between immune response and lipid metabolism ?
title L-carnitine: a partner between immune response and lipid metabolism ?
title_full L-carnitine: a partner between immune response and lipid metabolism ?
title_fullStr L-carnitine: a partner between immune response and lipid metabolism ?
title_full_unstemmed L-carnitine: a partner between immune response and lipid metabolism ?
title_short L-carnitine: a partner between immune response and lipid metabolism ?
title_sort l-carnitine: a partner between immune response and lipid metabolism ?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365452/
https://www.ncbi.nlm.nih.gov/pubmed/18475566
http://dx.doi.org/10.1155/S0962935193000729
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