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Nitric oxide mediates interleukin-1 induced inhibition of glycosaminoglycan synthesis in rat articular cartilage

Interleek-1β (IL-1) is a key mediator of cartilage matrix degradation in osteoarthritis and rheumatoid arthritis. It was found that the IL-1-induced suppression of glycosaminoglycan (GAG) synthesis in rat articular cartilage occurred simultaneously with the accumulation of nitrite (a metabolite of n...

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Detalles Bibliográficos
Autores principales:	Järvinen, T. A. H., Moilanen, T., Järvinen, T. L. N., Moilanen, E.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1995
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365616/ https://www.ncbi.nlm.nih.gov/pubmed/18475625 http://dx.doi.org/10.1155/S0962935195000184

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