Cargando…

IL-6-mediated MHC class II induction on RIN-5AH insulinoma cells by IFN-γ occurs via the G-protein pathway

Major histocompatibility complex (MHC) class II antigen expression has been implicated in the pathogenesis of autoimmune type 1 diabetes. In this study we examined the role of various cytoldnes that may induce MHC class II surface antigen expression, using the rat insulinoma line RIN-5AH as a pertin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vassiliadis, S., Papadopoulos, G. K.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1995
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365654/ https://www.ncbi.nlm.nih.gov/pubmed/18475668 http://dx.doi.org/10.1155/S0962935195000615

Ejemplares similares

Intratumoral Hypoxia Reduces IFN-γ–Mediated Immunity and MHC Class I Induction in a Preclinical Tumor Model
por: Murthy, Aditi, et al.
Publicado: (2019)

Both IFN-γ and IL-4 Induce MHC Class II Expression at the Surface of Mouse Pro-B Cells
por: Lombard-Platet, Suzanne, et al.
Publicado: (1997)

Investigation of intracellular signals generated by γ-interferon and IL-4 leading to the induction of class II antigen expression
por: Vassiliadis, S., et al.
Publicado: (1993)

IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments
por: Vardjan, Nina, et al.
Publicado: (2012)

MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids
por: Pickles, Oliver J., et al.
Publicado: (2023)

Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes
por: Vlková, Veronika, et al.
Publicado: (2014)

Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease
por: He, Tingyan, et al.
Publicado: (2023)

Genetic and commensal induction of IL-18 drive intestinal epithelial MHCII via IFNγ
por: Van Der Kraak, L. A., et al.
Publicado: (2021)

El Rin : historia, mitos y realidades /
por: Febvre, Lucien, 1878-1956
Publicado: (2004)

Schistosoma japonicum Soluble Egg Antigens Attenuate IFN-γ-Induced MHC Class II Expression in RAW 264.7 Macrophages
por: Tang, Gui-Xia, et al.
Publicado: (2012)

MHC-class-II are expressed in a subpopulation of human neural stem cells in vitro in an IFNγ–independent fashion and during development
por: Vagaska, B., et al.
Publicado: (2016)

Novel members of quinoline compound family enhance insulin secretion in RIN-5AH beta cells and in rat pancreatic islet microtissue
por: Orfi, Z., et al.
Publicado: (2017)

Inducible IFN-γ Expression for MHC-I Upregulation in Devil Facial Tumor Cells
por: Ong, Chrissie E. B., et al.
Publicado: (2019)

IFNγ producing CD8(+) T cells modified to resist major immune checkpoints induce regression of MHC class I-deficient melanomas
por: Buferne, Michel, et al.
Publicado: (2015)

The role of IL-12, IL-23 and IFN-γ in immunity to viruses
por: Novelli, Francesco, et al.
Publicado: (2004)

Induction of IFN-αβ enables Listeria monocytogenes to suppress macrophage activation by IFN-γ
por: Rayamajhi, Manira, et al.
Publicado: (2010)

GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease
por: Chuang, Huai-Chia, et al.
Publicado: (2018)

Class A CpG oligodeoxynucleotide inhibits IFN‐γ‐induced signaling and apoptosis in lung cancer
por: Teranishi, Shuhei, et al.
Publicado: (2020)

IFNγ-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of Insulitis but Is Not Required for Diabetogenic CD4(+) T Cell Migration
por: Scott, Nicholas A., et al.
Publicado: (2018)

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells
por: Liu, Yuying, et al.
Publicado: (2017)

In Vitro Induction of Regulatory CD4(+)CD8α(+) T Cells by TGF-β, IL-7 and IFN-γ
por: Van Kaer, Luc, et al.
Publicado: (2013)

Impaired IL-23–dependent induction of IFN-γ underlies mycobacterial disease in patients with inherited TYK2 deficiency
por: Ogishi, Masato, et al.
Publicado: (2022)

In Vivo Priming of Cd4 T Cells That Produce Interleukin (Il)-2 but Not IL-4 or Interferon (Ifn)-γ, and Can Subsequently Differentiate into IL-4–Or IFN-γ–Secreting Cells
por: Wang, Xiaowen, et al.
Publicado: (2001)

The destructive action of IL-1alpha and IL-1beta in IDDM is a multistage process: evidence and confirmation by apoptotic studies, induction of intermediates and electron microscopy.
por: Vassiliadis, S, et al.
Publicado: (1999)

N-Octanoyl-Dopamine inhibits cytokine production in activated T-cells and diminishes MHC-class-II expression as well as adhesion molecules in IFNγ-stimulated endothelial cells
por: Hofmann, Björn B., et al.
Publicado: (2019)

IFN-γ and CIITA modulate IL-6 expression in skeletal muscle
por: Adhikari, Abhinav, et al.
Publicado: (2020)

Human IL-23 is essential for IFN-γ-dependent immunity to mycobacteria
por: Philippot, Quentin, et al.
Publicado: (2023)

MHC Class II Expression in Human Basophils: Induction and Lack of Functional Significance
por: Voskamp, Astrid L., et al.
Publicado: (2013)

Predictive Value of Serum IFN-γ inducible Protein-10 and IFN-γ/IL-4 Ratio for Liver Fibrosis Progression in CHB Patients
por: Wang, Yadong, et al.
Publicado: (2017)

IL-11 prevents IFN-γ-induced hepatocyte death through selective downregulation of IFN-γ/STAT1 signaling and ROS scavenging
por: Miyawaki, Akimitsu, et al.
Publicado: (2019)

Antigen presentation by liposomes bearing class II MHC and membrane IL-1.
por: Bakouche, O., et al.
Publicado: (1990)

IL-33 promotes MHC class II expression in murine mast cells
por: Ito, Tomonobu, et al.
Publicado: (2015)

Serum concentration of IL-6, IL-2, TNF-α, and IFNγ in Vitiligo patients
por: Singh, Suman, et al.
Publicado: (2012)

Expressions of IL4, IL10, and IFNγ cytokines genes during bacterial mastitis
por: Faaz, Rana A., et al.
Publicado: (2022)

IL-4, IL-13 and IFN-γ -induced genes in highly purified human neutrophils
por: Kummola, Laura, et al.
Publicado: (2023)

International chemical identifier for reactions (RInChI)
por: Grethe, Guenter, et al.
Publicado: (2013)

International chemical identifier for reactions (RInChI)
por: Grethe, Guenter, et al.
Publicado: (2018)

Characterization of RIN Isoforms and Their Expression in Tomato Fruit Ripening
por: Slugina, Maria A., et al.
Publicado: (2021)

Insulinoma
por: Carral Garrido, Margarita
Publicado: (1997)

Recipients with In Utero Induction of Tolerance Upregulated MHC Class I in the Engrafted Donor Skin
por: Chen, Jeng-Chang, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_prkqb2tehoo2432cidlb3vhgbt