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Abrogation of mercuric chloride-induced nephritis in the Brown Norway rat by treatment with antibodies against TNFα
HgCl(2) induces an autoimmune disease in the Brown Norway rat characterized by synthesis of autoantibodies (mainly, anti-GBM Abs), severe proteinuria and interstitial nephritis. Also, HgCl(2)- injected rats develop glomerular cell infiltrates consisting of ED1(+) cells (monocyte/macrophage), startin...
Autores principales: | Molina, A., Sánchez-Madrid, F., Bricio, T., Martín, A., Escudero, E., Alvarez, V., Mampaso, F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365666/ https://www.ncbi.nlm.nih.gov/pubmed/18475678 http://dx.doi.org/10.1155/S0962935195000718 |
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