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Cytotoxicity towards human endothelial cells, induced by neutrophil myeloperoxidase: protection by ceftazidime
We investigated the effects of the antibiotic ceftazidime (CAZ) on the cytolytic action of the neutrophil myeloperoxidase–hydrogen peroxide–chloride anion system (MPO/H(2)O(2)/Cl(−)). In this system, myeloperoxidase catalyses the conversion of H(2)O(2) and CI(−) to the cytotoxic agent HOCl. Stimulat...
Autores principales: | Mathy-Hartert, M., Deby-Dupont, G., Deby, C., Jadoul, L., Vandenberghe, A., Lamy, M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365676/ https://www.ncbi.nlm.nih.gov/pubmed/18475677 http://dx.doi.org/10.1155/S0962935195000706 |
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