Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency

The MutS-based mismatch repair (MMR) system has been conserved from prokaryotes to humans, and plays important roles in maintaining the high fidelity of genomic DNA. MutS protein recognizes several different types of modified base pairs, including methylated guanine-containing base pairs. Here, we l...

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Detalles Bibliográficos
Autores principales: Taira, Kentaro, Nakamura, Shintaro, Nakano, Khota, Maehara, Daisuke, Okamoto, Keinosuke, Arimoto, Sakae, Loakes, David, Worth, Leroy, Schaaper, Roel M., Seio, Kohji, Sekine, Mitsuo, Negishi, Kazuo, Negishi, Tomoe
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365708/
https://www.ncbi.nlm.nih.gov/pubmed/18243250
http://dx.doi.org/10.1016/j.mrfmmm.2007.12.009

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