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Inhibition of the production of mediators of inflammation by corticosteroids is a glucocorticoid receptor-mediated process

In order to find an explanation for corticosteroid resistance we assessed whether inhibition by dexamethasone (DEX) of the stimulated production of TNF-∝, IL-6, PGE(2) and LTB(4) by peripheral blood mononuclear cells (MNC) depends on binding to the glucocorticoid receptor (GR), and whether it is det...

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Detalles Bibliográficos
Autores principales: Madretsma, G. S., Dijk, A. P. M. van, Tak, C. J. A. M., Wilson, J. H. P., Zijlstra, F. J.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1996
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365783/
https://www.ncbi.nlm.nih.gov/pubmed/18475705
http://dx.doi.org/10.1155/S0962935196000166