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Effects of anti-inflammatory drugs on fever and neutrophilia induced by Clostridium difficile toxin B

This study investigated the ability of Clostridium difficile toxin B, isolated from the VPI 10463 strain, to induce fever and neutrophilia in rats. Intravenous injection of toxin B (0.005–0.5 μg/kg) evoked a dose-dependent increase in body temperature. The febrile response to 0.5 μg/kg of the toxin...

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Detalles Bibliográficos
Autores principales:	Cardoso, R. A., Filho, A. A. Melo, Melo, M. C. C., Lyerly, D. M., Wilkins, T. D., Lima, A. A. M., Ribeiro, R. A., Souza, G. E. P.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1996
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365796/ https://www.ncbi.nlm.nih.gov/pubmed/18475713 http://dx.doi.org/10.1155/S0962935196000245

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