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Tumor necrosis factor, interleukin-1 and interleukin-8 mediate the nociceptive activity of the supernatant of LPS-stimulated macrophages

It has been suggested that the supernatant of LPSstimulated macrophages (macrophage nociceptive factor, MNF) promotes nociception in mice. Intraperitoneal administration of MNF induced dose-related writhing, which reached a plateau between 18 and 26 min after injection and decreased within 60 min. T...

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Detalles Bibliográficos
Autores principales:	Thomazzi, S. M., Ribeiro, R. A., Campos, D. I., Cunha, F. Q., Ferreira, S. H.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 1997
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365829/ https://www.ncbi.nlm.nih.gov/pubmed/18472820 http://dx.doi.org/10.1080/09629359791686

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