(1→3)-β-D-glucanemia in deep mycosis

Factor G, a coagulation proenzyme of the Japanese horseshoe crab (Tachypleus tridentatus), is extremely sensitive to (1→3)-β-D-glucan, which is a characteristic cell-wall constituent of fungi. Using this factor and by a digestion study with (1→3)-β-D-glucan, we showed that blood from patients with d...

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Detalles Bibliográficos
Autor principal: Obayashi, Taminori
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365870/
https://www.ncbi.nlm.nih.gov/pubmed/18472857
http://dx.doi.org/10.1080/09629359791604
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author Obayashi, Taminori
author_facet Obayashi, Taminori
author_sort Obayashi, Taminori
collection PubMed
description Factor G, a coagulation proenzyme of the Japanese horseshoe crab (Tachypleus tridentatus), is extremely sensitive to (1→3)-β-D-glucan, which is a characteristic cell-wall constituent of fungi. Using this factor and by a digestion study with (1→3)-β-D-glucan, we showed that blood from patients with deep m ycosis contains the glucan. It was detected in 39 out of 41 fungal febrile episodes (sensitivity 90%), but in none of the 59 nonfungal febrile episodes (specificity 100%).
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spelling pubmed-23658702008-05-12 (1→3)-β-D-glucanemia in deep mycosis Obayashi, Taminori Mediators Inflamm Research Article Factor G, a coagulation proenzyme of the Japanese horseshoe crab (Tachypleus tridentatus), is extremely sensitive to (1→3)-β-D-glucan, which is a characteristic cell-wall constituent of fungi. Using this factor and by a digestion study with (1→3)-β-D-glucan, we showed that blood from patients with deep m ycosis contains the glucan. It was detected in 39 out of 41 fungal febrile episodes (sensitivity 90%), but in none of the 59 nonfungal febrile episodes (specificity 100%). Hindawi Publishing Corporation 1997-11 /pmc/articles/PMC2365870/ /pubmed/18472857 http://dx.doi.org/10.1080/09629359791604 Text en Copyright © 1997 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Obayashi, Taminori
(1→3)-β-D-glucanemia in deep mycosis
title (1→3)-β-D-glucanemia in deep mycosis
title_full (1→3)-β-D-glucanemia in deep mycosis
title_fullStr (1→3)-β-D-glucanemia in deep mycosis
title_full_unstemmed (1→3)-β-D-glucanemia in deep mycosis
title_short (1→3)-β-D-glucanemia in deep mycosis
title_sort (1→3)-β-d-glucanemia in deep mycosis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365870/
https://www.ncbi.nlm.nih.gov/pubmed/18472857
http://dx.doi.org/10.1080/09629359791604
work_keys_str_mv AT obayashitaminori 13bdglucanemiaindeepmycosis

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