Mapping the Genetic Architecture of Gene Expression in Human Liver

Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits. Therefore, identifying the molecular phenotypes that vary in response to changes in DNA a...

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Detalles Bibliográficos
Autores principales: Schadt, Eric E, Molony, Cliona, Chudin, Eugene, Hao, Ke, Yang, Xia, Lum, Pek Y, Kasarskis, Andrew, Zhang, Bin, Wang, Susanna, Suver, Christine, Zhu, Jun, Millstein, Joshua, Sieberts, Solveig, Lamb, John, GuhaThakurta, Debraj, Derry, Jonathan, Storey, John D, Avila-Campillo, Iliana, Kruger, Mark J, Johnson, Jason M, Rohl, Carol A, van Nas, Atila, Mehrabian, Margarete, Drake, Thomas A, Lusis, Aldons J, Smith, Ryan C, Guengerich, F. Peter, Strom, Stephen C, Schuetz, Erin, Rushmore, Thomas H, Ulrich, Roger
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365981/
https://www.ncbi.nlm.nih.gov/pubmed/18462017
http://dx.doi.org/10.1371/journal.pbio.0060107

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